杜长波++裴玉梅

[摘要] 目的 分析研讨酪酸梭菌二联活菌散对小儿肺炎继发性腹泻疾病的临床疗效。 方法 此研究为前瞻性研究，采用随机抽签方式，从该院2015年3月—2016年6月期间收治的小儿肺炎继发性腹泻疾病者中，方便抽取90例患者纳入到讨论中，90例患者按入院单双顺序分45例对照组（思密达药物治疗）和45例研究组（酪酸梭菌二联活菌散药物治疗），对比讨论两组患儿临床治疗状况。结果 研究组治疗总疗效88.89%比对照组73.33%高，组间数据差异有统计学意义（P<0.05）。对比两组患儿肺炎治疗时间、腹泻持续时间、住院时间，研究组（4.2±1.7）d、（2.2±1.1）d、（4.5±2.0）d比对照组（6.9±2.2）d、（4.5±1.5）d、（7.2±2.3）d短，组间数据差异有统计学意义（P<0.05）。结论 临床治疗小儿肺炎继发性腹泻疾病可考虑给予酪酸梭菌二联活菌散药物进行治疗，疗效突出，患儿肠黏膜屏障得到修复，其腹泻症状得到快速缓解，肺炎疗程得到缩短，临床可大力进行推广和应用。

[关键词] 腹泻；肺炎；继发性；酪酸梭菌二联活菌散；思密达

[中图分类号] R725 [文献标识码] A [文章编号] 1674-0742（2017）05（b）-0122-03

[Abstract] Objective To analyze the clinical curative effect of bivalent of clostridium butyricum powder in treatment of pediatric pneumonia secondary to diarrhea. Methods 90 cases of children with pneumonia secondary to diarrhea admitted and treated in our hospital from March 2015 to June 2016 were convenient selected and randomly divided into two groups with 45 cases in each， the control group were treated with dioctahedral smectite agents， while the research group were treated with bivalent of clostridium butyricum powder， and the clinical treatment situation were compared between the two groups. Results The total curative effect in the research group was higher than that in the control group（88.89% vs 73.33%）， and the difference between groups was statistically significant（P<0.05）， and the pneumonia treatment time， diarrhea duration and length of stay in the research were shorter than those in the control group[（4.2±1.7）d， （2.2±1.1）d， （4.5±2.0）d vs （6.9±2.2）d， （4.5±1.5）d， （7.2±2.3）d]， and the differences between groups were statistically significant（P<0.05）. Conclusion We can consider the bivalent of clostridium butyricum powder in treatment of pediatric pneumonia secondary to diarrhea and the curative effect is outstanding， which can repair the intestinal mucosa barrier of children， rapidly relieve the diarrhea symptoms and shorten the treatment course of pneumonia， and it can be greatly promoted and applied in clinic.

[Key words] Diarrhea； Pneumonia； Secondary； Bivalent of clostridium butyricum powder； Dioctahedral smectite

婴幼儿时期较为常見的一种疾病则为肺炎疾病[1-2]，属于造成我国婴幼儿死亡的首先因素，对小儿健康造成严重威胁。引发小儿肺炎疾病的原因为微生物，多因感染病毒或细菌，临床多给予抗生素进行治疗。用抗生素治疗中，继发性腹泻疾病发病率较高。此症状的出现则加大了患儿病情状况，也加大了出现其他类型获得性感染的可能性，其住院时间得到延长，加大了其医疗费用开支。疾病早期给予患儿微生态制剂进行治疗，可适当补充益生菌，快速提升人体肠道中益生菌质量和数量，调整和保持小儿肠道微生态处于平衡状态，达到治疗和预防的目的。为此，此研究将2015年3月—2016年6月期间该院90例患者分组研讨，其目的在于酪酸梭菌二联活菌散对小儿肺炎继发性腹泻疾病的临床疗效，现报道如下。

1 资料与……