刘一星

[摘要] 目的 分析肝血管瘤治疗中不同介入栓塞方法的应用及效果对照。方法 方便收集山东省菏泽市立医院介入科2015年5月—2017年1月收治的90例肝血管瘤患者并随机分组。单纯栓塞组用平阳霉素碘化乳剂栓塞，联合栓塞组在单纯栓塞组基础上进行明胶海绵颗粒栓塞。比较两组患者肝血管瘤疗效；介入栓塞并发症发生率；治疗前和治疗后患者总胆汁酸情况的差异。结果 联合栓塞组患者肝血管瘤疗效95.56%高于单纯栓塞组82.22%（P<0.05）。联合栓塞组介入栓塞并发症发生率33.33%低于单纯栓塞组40.00%，但两者之间差异无统计学意义（P>0.05）；治疗前两组总胆汁酸情况比较数据接近（P>0.05）；治疗后联合栓塞组总胆汁酸降低显著优于单纯栓塞组（P<0.05）。结论 肝血管瘤治疗中在平阳霉素碘化乳剂栓塞基础上进行明胶海绵颗粒栓塞的应用及效果优于单纯采用平阳霉素碘化乳剂栓塞，可提高治疗效果，降低总胆汁酸水平，值得推广。

[关键词] 肝血管瘤治疗；不同介入栓塞方法；应用效果对照

[中图分类号] R735 [文献标识码] A [文章编号] 1674-0742（2017）05（b）-0020-03

[Abstract] Objective To analyze the comparison of application effect of different intervention embolization methods in treatment of hepatic hemangioma. Methods Convenient selection 90 cases of patients with hepatic hemangioma admitted and treated in our hospital from May 2015 to January 2017 were selected and randomly divided into two groups， the simple embolization group adopted the embolization with pingyangmycin lipiodol emulsion， while the combined embolization group adopted the embolization with gelatin sponge particles on the basis of the simple group， and the curative effect of hepatic hemangioma， incidence rate of interventional embolization complications and the total bile acid of patients before and after treatment were compared between the two group. Results The curative effect of hepatic hemangioma in the combined group was higher than that in the simple group（95.56% vs 82.22%）（P<0.05）， and the incidence rate of intervention embolization in the combined group was lower than that in the simple group（33.33% vs 40.00%）， and there was no obvious difference between the two （P>0.05）， before treatment， the total bile acid of the two groups was similar（P>0.05）， after treatment， the total bile acid decrease in the combined group was obviously better than that in the simple group（P<0.05）. Conclusion The application effect of embolization with gelatin sponge particles on the basis of embolization with pingyangmycin lipiodol emulsion in treatment of hepatic hemangioma is better than that of simple embolization with pingyangmycin lipiodol emulsion， which can improve the treatment effect and reduce the total bile acid level， and it is worth promotion.

[Key words] Hepatic hemangioma treatment； Different intervention embolization methods； Comparison of application effect

肝血管瘤是一種肝脏良性肿瘤，患者没有典型症状，其中以海绵状血管瘤多见。但病情进一步进展之后，患者可出现腹部一系列不适症状，甚至可导致肝血管瘤破裂，导致患者死亡[1]，危害性大。目前关于肝血管瘤发病机制尚未明确，研究表明，肝血管瘤和雌激素水平异常、肝内血管发育相关[2]。传统多对肝血管瘤患者采取开放手术治疗，由于带来较大的创伤，已经逐渐不被患者所接受。近些年来，随着各种微创技术、介入技术不断发展，介入栓塞方法已在肝血管瘤治疗中广泛应用，该研究收集山东省菏泽市立医院介入科2015年5月—2017年1月收治的90例肝血管瘤患者并随机分组，分析了肝血管瘤治疗中不同介入栓塞方法的应用及效果对照，现报道如下。 ……