蔡文灵

【摘 要】 目的：观察结核丸联合西药治疗结核性胸膜炎的临床疗效。方法：选取512例结核性胸膜炎患者，随机分为对照组和观察组各256例。对照组采取西药治疗，接受常规抗结核治疗方案2HRZE/7HR；观察组在西药治疗的基础上加用结核丸。治疗后比较两组临床疗效。结果：观察组的胸腔积液完全吸收平均时间为（15±4）d，短于对照组的（25±3）d，差异具有统计学意义（P<0.01）；观察组的胸膜厚度为（3.56±2.30）mm，优于对照组的（5.04±2.11）mm（P<0.01）。观察组总有效率为94.9%，高于对照组的87.1%，差异具有统计学意义（P<0.01）。结论：结核丸联合西药治疗结核性胸膜炎疗效显著，可有效减少胸膜肥厚，提高临床治愈率，值得临床推广应用。

【关键词】 结核性胸膜炎；结核丸；西药治疗

【中图分类号】R521.7 【文献标志码】 A 【文章编号】1007-8517（2017）09-0104-03

Tuberculosis Pills Combined with Western Medicine in Treating Tuberculous Pleurisy：256 Cases

CAI Wenling

The Seventh People's Hospital of Luohe， Luohe 462000，China

Abstract：Objective To observe the clinical curative effect oftuberculosis pills combined with western medicine in treating tuberculous pleurisy. Methods 512 patients withtuberculous pleurisy were randomly divided into control group and observation group， 256 cases in each group.The control group were treated with western medicine alone and received routine 2HRZE / 7HR. The observation group were treated with tuberculosis pills on the basis of western medicine.After the treatment，the clinical efficacy of the two groups was observed.Results The mean time of complete absorption of pleural effusion in the observation group was （15±4） d， which was significantly longer than that of the control group （25±3）d， with significant difference （P<0.01）. The pleural thickness of the observation group （3.56±2.30）mm was significantly lower than that of the control group （5.04±2.11）mm（P<0.01）. The total effective rate of observation group was 94.9%， which was significantly higher than the total effective rate of the control group 87.1%， with significant difference（P<0.01 ）. Conclusion Tuberculosis pill combined with western medicine is effective in treating tuberculous pleurisy， effectively reducing pleural thickening and improving the clinical cure rate.

Keywords：Tuberculous Pleurisy； Tuberculosis Pills； Western Medicine Treatment

结核性胸膜炎是由结核分枝杆菌及其代谢产物进入处于高敏状态的胸膜腔引起的胸膜炎症，主要表现为全身中毒症状和胸腔积液所致的局部症状[1]。胸水吸收易造成胸膜肥厚，影响肺功能，甚至威胁患者生命安全[2]。因此，在结核性胸膜炎的治疗过程中，促进胸腔积液的吸收、抑制胸膜肥厚至关重要。笔者运用结核丸联合西药治疗结核性胸膜炎，取得了良好的临床效果，现报道如下。

1 资料与方法

1.1 一般资料 选取我院2009年1月至2016年5月收治的512例結核性胸膜炎患者，均确诊为结核性胸膜炎。随机分为对照组和观察组，各256例。对照组男145例，女111例，平均年龄（36.1±5.8）岁；观察组男142例，女114例，平均年龄（35.4±7.3）岁。两组一般资料比较差异无统计学意义（P>0.05），具有可比性。本研究经医院伦理委员会批准，所有患者均签署知情同意书。

1.2 治疗方法

1.2.1 胸腔积液处理 两组均根据临床B超检查定位情况，对胸腔积液进行抽取。抽液方法相同，根据胸腔积液情况1周抽取1～2次，均不进行胸腔内注药。……