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Epigenetic Methods in Neuroscience Research published

2017-01-12

中国现代神经疾病杂志 2017年2期

Epigenetic Methods in Neuroscience Research published

Epigenetic Methods in Neuroscience Research(ISBN:978-1-4939-2753-1,eBook ISBN:978-1-4939-2754-8)was published by Springer in 2016.The editor of this book is Nina N.Karpova,Neuroscience Center,University of Helsinki.

This volume presents state⁃of⁃the⁃art methods for reliable detection of epigenetic changes in the nervous system.Epigenetic Methods in Neuroscience Researchguides readers through methods for the analyses of chromatin remodeling,transposable elements, non⁃coding RNAs,such as micro RNAs(miRNAs),and circadian oscillations,including:analysis of DNA methylation in neuronal and glial cells or small tissue samples;sensitive method for quantification of alternative methylated forms of cytosines by liquid chromatography/mass spectrometry;affinity⁃based detection of modified cytosines by immunohistochemistry or methylated DNA immunoprecipitation;chromatin immunoprecipitation(ChIP);miRNA high⁃throughput profiling and the in situ detection of miRNA subtle expression in the brain;analysis of genes with alternative 3'untranslated regions(3'UTRs);and the cite⁃specific delivery of chromatin⁃modifying drugs.Written in the popular Neuromethods series style,chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.

Concise and easy⁃to⁃use,Epigenetic Methods in Neuroscience Researchprovides multidisciplinary epigenetic approach to study genome,and neural,plasticity that will help the reader to successfully address the challenges associated with neurodevelopmental, psychiatric,and neurodegenerative disorders.

The price of eBook is 79.72€,and hardcover is 94.99€.Visit link.springer.com for more information.