黄富礼，邹家凤，吴刚，王舟强，郭正毅，黄永茂△（.泸州医学院附属医院感染科，四川泸州646000；.泸州市疾病预防控制中心，四川646000；.泸州医学院附属医院信息科，四川泸州646000）

·论著·

某院2003～2015年住院疟疾患者特点分析*

黄富礼1，邹家凤2，吴刚1，王舟强3，郭正毅3，黄永茂1△
（1.泸州医学院附属医院感染科，四川泸州646000；2.泸州市疾病预防控制中心，四川646000；3.泸州医学院附属医院信息科，四川泸州646000）

目的分析泸州医学院附属医院2003～2015年疟疾住院患者临床资料及流行病学特点，为临床诊治及预防提供理论支撑。方法回顾性分析近13年来该院收治的53例疟疾住院患者的临床资料，分析其人口学特点、临床表现及实验室检查结果，并分析其流行趋势与特点。结果近13年来，医院输入性疟疾患者数量逐年递增，共53例患者，其中男女比例为25.5∶1，平均年龄为（38.4±13.2）岁。发病高峰在每年春节前1个月及6月份和10月份左右。其中恶性疟41例，间日疟9例，未分型3例。100%（29/29）患者降钙素原水平升高，中性粒细胞比例升高者达87%（46/53）。结论医院输入性疟疾患者有逐年增多趋势，应重视输入性疟疾特别是恶性疟的诊治，加强疟疾感染者降钙素原的监测及感染的控制。

疟疾；降钙素；住院病人；数据收集；感染

【Abstract】Objective To analyze the clinicaland epidemiological characteristics of malaria inpatients in our hospital during 2003-2015 in order to provide a theoreti calbasis for its clinicaldiagnosis，treat ment and prevention.Methods The clinicaldata of hospitalized patients with malaria in our hospital during the recent13 years were retrospectively analyzed，including the demographic characteristics，clinicalma nifestations and laboratory tests results.And its epidemic trends and characteristics were analyzed too.Results During these 13 years，the imported malaria patients were increased year by year，therewere 53 cases of malaria，themale-to-female ratiowas 25.5∶1，the age averaged（38.4±13.2）years old.The onsetpeak was at1month before the Spring Festival every year，June and October.Among them，41 cases were malignant malaria，9 cases were vivax malaria and 3 caseswere un known type.The procalcitonin（PCT）level was increased in 100%（29/29）of the patients，the patientswith increased neutrophil proportion reached 87%（46/53）.Conclusion The hospital imported malaria patients show the increasing trend year by year，the diagnosis and treatment of imported malaria，especially falciparum malaria，should be paid more attention to，PCT monitoring and infection control in themalaria patients should be strengthened.

【Key words】Malaria；Calcitonin；Inpatients；Data collection；Infection

尽管在世界范围内，疟疾的发病率与死亡率都明显下降，特别是在非洲以外的地区［1］，但全球仍有1.2亿人处于疟疾感染高风险中。2014年全球疟疾报告显示，2013年全球有近584 000人死亡［2］。中国从近几年疫情报告显示，很多地方已没有本土疟疾的发生，而以输入性疟疾为主。……