镇静治疗对颅脑外伤高颅压患者预后的影响
2016-08-06贺兰兰镇江市第一人民医院急诊科江苏镇江212000
贺兰兰(镇江市第一人民医院急诊科,江苏 镇江 212000)
镇静治疗对颅脑外伤高颅压患者预后的影响
贺兰兰
(镇江市第一人民医院急诊科,江苏 镇江 212000)
目的 探讨镇静治疗对颅脑外伤高颅压患者预后的影响。方法 研究对象选取我院近年来收治颅脑外伤高颅压患者共80例,采用随机数字表法分为对照组和治疗组,每组40例。对照组患者采用大骨瓣减压术治疗,治疗组患者则在术前给予右美托咪定治疗;比较两组患者术后不同时间点Ramsay镇静评分,颅内压水平及格拉斯哥预后(GCS)评分。结果 治疗组患者术后不同时间点Ramsay评分和颅内压水平均显著低于对照组,差异有统计学意义(P<0.05);治疗组患者术后12个月GCS评分显著高于对照组,差异有统计学意义(P<0.05)。结论 镇静治疗用于颅脑外伤高颅压患者可有效提高镇静程度,降低颅内压水平,并有助于改善远期预后。
镇静治疗;颅脑外伤;高颅压;预后
[Abstract]Objective To investigate the effects of sedation treatment on the prognosis of patients with intracranial hypertension after craniocerebral trauma. Methods 80 patients with intracranial hypertension after craniocerebral trauma were chosen in recent year in our hospital and randomly divided into 2 groups including control group (40 patients) with large bone flap decompression operation used alone and observation group (40 patients) with dexmedetomidine treatment on the basis of control group; and the Ramsay sedation score, intracranial pressure level and glasgow coma scale (GCS) at different time points after operation of both groups were compared. Results The Ramsay sedation score and intracranial pressure level at different time points after operation of observation group was significant better than control group(P<0.05). The GCS scores in 12 months after operation of observation group was significant better than control group(P<0.05). Conclusion Sedation treatment on the prognosis of patients with intracranial hypertension after craniocerebral trauma can efficiently higher sedation degree, decrease the levels of intracranial pressure and be helpful to improve the long-term prognosis.
[Key words]Sedation treatment; Craniocerebral trauma; Intracranial hypertension; Prognosis
本次研究以我院近年来收治颅脑外伤高颅压患者共80例作为研究对象,采用随机数字表法分为对照组和治疗组,每组40例。对照组患者采用大骨瓣减压术治疗,治疗组患者则在术前给予右美托咪定治疗;比较两组患者术后不同时间点Ramsay镇静评分,颅内压水平及格拉斯哥预后(GCS)评分,探讨镇静治疗对颅脑外伤高颅压患者预后的影响。
1 资料与方法
1.1 临床资料:研究对象选取我院2013年4月至2014年4月收治颅脑外伤高颅压患者共80例,美国麻醉协会(ASA)评级Ⅰ~Ⅱ级,格拉斯哥昏迷评分(GCS) 9~15分,排除合并呼吸系统疾病及严重肝肾功能障碍者。……
