库肯勃瘤误诊为原发卵巢癌6例分析
2016-01-28高蔚梅北京市顺义区妇幼保健院功能科北京101300
高蔚梅(北京市顺义区妇幼保健院功能科,北京 101300)
库肯勃瘤误诊为原发卵巢癌6例分析
高蔚梅*
(北京市顺义区妇幼保健院功能科,北京 101300)
目的 探讨库肯勃瘤(Krukenberg tumor)误诊漏诊的常见原因,为降低误诊、漏诊率提供对策。方法 对我院经病理证实的6例原发于胃肠道的卵巢转移癌患者的临床资料进行回顾分析,包括就诊及胃肠镜检查资料等,归纳总结误诊原因并制定针对性解决措施。结果 库肯勃瘤临床表现缺乏特异性,转移症状常常掩盖原发症状。接诊医师对该病认识不足,思路狭窄,考虑局限,诊断缺乏专业性和警惕性是误诊主要原因。结论 在全面详细的病史询问、细致规范的体格检查和常规B超检查基础上,必要时增加内镜检查、定位活检和针对性实验室检查可提高检出率,降低误诊率。
库肯勃瘤;卵巢癌;临床分析
[Abstract]Objective To investigate the common causes of misdiagnosed Krukenberg tumor, in order to provide strategies to reduce misdiagnosis.
Methods The clinical and gastrointestinal endoscopy data of 6 cases of metastatic ovarian cancer originated from gastrointestinal carcinoma. The causes of misdiagnosis were summarized, and corresponding solutions were provided. Results Krukenberg tumor will usually be misdiagnosed for lack of specific clinical manifestation, andmetastasis symptomswill conceal the primary symptoms. Clinician's lack of professional knowledge and vigilance are main reasons for misdiagnosis. Conclusions Comprehensive collection of medical history and detailed physical examination, as well as ultrasonography examination,with increased endoscopy and biopsy examination when necessary, can improve the detection rate.
[Key words]Krukenbergtumor; Ovarian cancer; Clinical analysis
1 临床资料
1.1 一般资料:本组6例患者均符合库肯勃瘤诊断标准,其中5例为胃癌卵巢转移,1例为结肠癌(回盲部)卵巢转移。66.7%(4/6)的患者有胃肠道病史,其中慢性胃炎病史3例,慢性阑尾炎病史1例。6例患者年龄23~51岁,中位年龄35岁。首次我院就诊前病程15 d~1年。
1.2 发病情况:6例患者首次均就诊于我院妇科,其中3例因盆腔包块、腹水就诊,1例因不明原因腹水、下腹胀痛就诊,1例因月经紊乱、阴道不规则出血、原发不孕就诊,1例要求取环体检时发现卵巢囊实性包块就诊。6例患者B超检查均提示盆腔包块或卵巢囊实性肿物伴不同程度腹水。3例术前胃镜检查活检诊断为印戒细胞癌,1例术前肠镜检查提示“升结肠回盲处肠壁增厚水肿”,活检提示炎症改变,术后病理证实为结肠癌(回盲部)卵巢转移。……
