冠状动脉多支病变患者心外膜脂肪层厚度与左房构型的关系

吕雪芬1,朱向明2,刘骏3,叶天舟3

(1.芜湖市第一人民医院超声科,安徽芜湖241000; 2.皖南医学院附属弋矶山医院超声科,安徽芜湖241001;3.芜湖市第一人民医院心内科,安徽芜湖241000)

【摘要】目的：评价冠状动脉多支病变患者心外膜脂肪层厚度和左房构型的相关性。方法：根据冠状动脉造影结果选择冠状动脉正常者26例为对照组，冠状动脉3支及3支以上病变组28例；超声心动图测量心外膜脂肪层厚度、左房内径(LAD)、左房容积(LAV)和左室射血分数(LVEF)，用体表面积标化出左房内径指数(LADi)和容积指数(LAVi)。比较两组心外膜脂肪层厚度及左房构型指标的差异，观察冠状动脉多支病变组心外膜脂肪层厚度与左房构型之间相关性。结果：冠状动脉多支病变组与对照组心外膜脂肪层厚度值分别为 (8.96±1.62)mm和(3.91±1.14)mm，冠状动脉多支病变组心外膜脂肪层厚度与LAV、LAVi增大(P<0.05)，心外膜脂肪层厚度与LAV、LAVi呈正相关。结论：冠状动脉多支病变组心外膜脂肪层厚度显著增加，并且能够反映左房构型改变的程度。

【关键词】超声心动描记术；冠状动脉疾病；心外膜脂肪组织；左心房

【文献标识码】【中图号】R 541.4A

DOI【】10.3969/j.issn.1002-0217.2015.02.027

文章编号：1002-0217(2015)02-0193-04

基金项目：国家级大学生创新创业训练计划(AH201310368021)

收稿日期：2014-06-10

作者简介：陈磊(1990-)，男，2010级预防医学本科生，(电话)18355358923，(电子信箱)9937755582@qq.com；

通讯作者袁慧，女，副教授，(电子信箱)yuanhui0553@163.com，.

Epicardial adipose tissue thickness and left atrial geometry pattern in patients with multiple coronary artery lesionsLÜXuefen,ZHUXiangming,LIUJun,YETianzhou

Department of Ultrasonography,Wuhu No.1 People′s Hospital,Wuhu 241000,China

Abstract【】Objective：To assess the relationship between epicardial adipose tissue thickness and left atrial geometry patterns in patients with multiple coronary artery lesions.Methods:Twenty-six patients with normal coronary artery were included as controls and 28 with coronary artery lesions of three or above as lesion group.The epicardial fat thickness,inner diameter of the left atrium(LAD),volume of the left atrium (LAV) and left ventricular ejection fraction (LVEF) were measured with echocardiography.The indices of the diameter and volume in relation to body surface area(BSA) (LADi and LAVi,respectively) were calculated.The two groups were compared regarding the parameters measured for determination of the relationship between the qpicardial fat thickiness and left atrial geometry pattern.Results:The thickness of epicardial adipose tissue was (8.96±1.62)mm for the lesion group and (3.91±1.14)mm for the controls.The epicardial fat thickness,LAV and LAVi were increased in patients with multiple coronary artery disease(P<0.05),and the fat thickness was positively related to LAV and LAVi.Conclusion:Significantly increased epicardial adipose tissue thickness is seen in patients with multiple coronary artery lesions,and this may be an indicator to reflect the left atrial geometry change.

【Key words】 echocardiography;coronary artery disease;epicardial adipose tissue;left atrium

内脏脂肪组织增加已被公认为是动脉粥样硬化性疾病的一个重要危险因素，心外膜脂肪层厚度是内脏脂肪组织的简易量化指标，与冠心病高危因素高度相关，超声测量心外膜脂肪层厚度可预测冠心病的存在并可反映冠状动脉病变程度，但心外膜脂肪层厚度与冠心病心脏构型改变的关系研究较少，本研究主要探讨冠状动脉多支病变患者心外膜脂肪层厚度变化以及其与左房构型之间的关系。……