田晓华 魏琴

[摘要] 目的 分析冠心病高黏滞血症患者采用红花黄色素氯化钠治疗的临床效果。方法 选择该院2013年7月—2014年7月收治的冠心病高黏滞血症患者50例，将其随机分成实验组和对照组各25例，对照组患者给予常规治疗，实验组患者在常规治疗的基础上给予红花黄色素氯化钠治疗。对两组患者的临床治疗效果和治疗前后的血液流变学指标变化情况进行比较分析。结果 实验组患者的临床治疗有效率高于对照组患者的临床治疗有效率，但是两组比较差异无统计学意义（P>0.05）；两组患者中，除对照组患者的全血还原粘度无明显变化外，两组其余各项血液流变学指标均显著低于治疗前（P<0.05）；治疗后，两组患者除纤维蛋白原含量和红细胞积压指标比较差异无统计学意义（P>0.05），其余各项指标比较差异均有统计学意义（P<0.05）。结论 在冠心病高黏滞血症患者的治疗中，应用红花黄色素氯化钠能取得比较理想的治疗效果。

[关键词] 冠心病高黏滞血症；红花黄色素氯化钠；临床效果

[中图分类号] R541.4 [文献标识码] A [文章编号] 1674-0742（2015）02（b）-0168-03

Analysis of the clinical effect of coronary heart disease with hyperviscosity syndrome in patients with application of safflor yellow and sodium chloride treatment

TIAN Xiaohua WEI Qin

Henan province Xinxiang First People's Hospitalpharmacy，Xinxiang， Henan Province， 453000，China

[Abstract] Objective to analyze clinical effect of coronary heart disease high viscosity sodium chloride treated by safflower yellow lag in patients with. Methods coronary heart disease in our hospital in 2013 July to select the 2014 July were 50 cases of patients with high viscosity and plasma， divided into the experimental group and the control group with 25 cases in each group， the control group were given routine treatment， patients in the experimental group in the conventional treatment based on the given saffloryellow sodium chloride treatment. Blood rheology before and after the two groups of patients with clinical effects and treatment of learning indicators of changes in comparative analysis. Results the clinical treatment of the experimental group were higher than that in the control group the effective rate of clinical treatment in patients with efficiency， but the difference between the two groups had no statistical significance（P > 0.05）； two patients in control group， the whole blood reduction viscosity in patients with no obvious change， two groups of the rest of the blood rheology indices were significantly lower than that of before treatment （P < 0.05）； after treatment， two groups of patients in addition to the content of fibrinogen and erythrocyte backlog index have no significant difference （P > 0.05）， the rest of the index difference was statistically significant （P < 0.05）. Conclusion in the treatment of coronary heart disease with hyperviscosity syndrome patients， sodium chloride application of safflor yellow can obtain ideal curative effect.

[Key words] Coronary heart disease with hyperviscosity syndrome； safflor yellow and sodium chloride； clinical effect

临床上高黏滞血症也被称为血液流变学异常，在冠心病患者中高黏滞血症的发生几率非常高，高黏滞血症的出现会让血流阻力增加，这样血液就会处在一个高凝状态，让血液循环受到比较严重的影响，进而导致心、肺、肾、脑等器官功能性障碍，出现缺血和缺氧等症状[1]。头痛、视觉紊乱、耳鸣和四肢麻木等是高黏滞血症的主要临床症状，会对患者的身体健康和生活质量造成比较严重的影响。通过查阅相关资料可知，红花黄色能让心肌供血得到有效改善，让血液粘稠度降低，扩张血管，对血小板的凝聚进行抑制[2]。该研……