多导睡眠监测仪在老年阻塞性睡眠呼吸暂停综合征中的应用
2015-08-29朱滢周英
朱滢++++++周英

[摘要] 目的 分析多导睡眠监测仪在老年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)中的应用价值。方法 收集2012年2月—2014年3月期间OSAHS的老年患者150例,作为OSAHS组。OSAHS患者又根据病情轻重分为轻、中、重组,纳入同时期健康志愿者50例作为对照组。采用多导睡眠监测仪对所有受试者进行睡眠监测,观察指标为AHI、LSAT、MAI、SaO2<90% T,比较组间差异。结果 老年OSAHS组患者AHI和MAI显著高于对照组,LSAT显著低于对照组,SaO2<90% T值则显著长于对照组,P<0.05。LSAT与AHI呈负相关(r=-0.569,P<0.05);MAI、SaO2<90% T与AHI呈正相关(r分别为0.569和0.697, P<0.05)。 结论 多导睡眠监测仪能有效检测老年OSAHS, LSAT、MAI、SaO2<90% T与AHI呈相关性,能用于OSAHS病情的辅助判断。
[关键词] 阻塞性睡眠呼吸暂停综合征;多导睡眠监测仪;老年
[中图分类号] R59 [文献标识码] A [文章编号] 1674-0742(2015)01(a)-0060-03
Application of Polysomnograph in Aged Patients with Obstructive Sleep Apnea Syndrome
ZHU Ying XU Dan
Department of Geriatrics, The first peoples Hospital of Yunnan Province,Kunming,650032,China
[Abstract] Objective To study the values of applying polysomnograph in aged patients with obstructive sleep apnea syndrome (OSAHS). Methods We enrolled 150 aged patients with OSAHS as the OSAHS group. According to the severity of OSAHS, these patients were further stratified in group of mild, moderate, and sever. Fifty healthy volunteers were enrolled as the control group. All subjects underwent sleep monitoring by using polysomnograph. Polysomnographic variables assessed among study groups included Apnea/Hypopnea index (AHI), lowest oxygen saturation (LSAT), mixed apnea index (MAI), and the time of oxygen saturation of less than 90%(SaO2<90%T). Results Compared to the control subjects, the OSAHS patients presented with significantly increased AHI and MAI, decreased LSAT, and prolonged SaO2<90%T values (P < 0.05, all four parameters). AHI was negatively correlated with LSAT (r=-0.569,P<0.05) and positivity correlated with MAI and SaO2<90%T (r=0.569 and 0.697, respectively,P<0.05). Conclusions Polysomnograph can effectively test OSAHS for aged patients, indicating correlations between LSAT、MAI、SaO2<90%T and AHI, and assisting the assessment of OSAHS severity.
[Key words] Obstructive sleep apnea syndrome; Polysomnograph, aged
阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是一种病因不明的睡眠呼吸疾病,临床表现为夜间睡眠打鼾伴呼吸暂停、白天嗜睡等。OSAHS是一种有潜在致死性的睡眠呼吸疾病,夜间低氧和高碳酸血症不仅会导致冠心病、高血压和脑血管疾病,还会引起夜间猝死。随着年龄的增长OSAHS发病率会明显升高,据统计老年人中OSAHS发病率高达20%~40%,降低了老年人的生活质量,严重威胁老年人的身心健康[1]。多导睡眠监测仪(Polyso mnography,PSG)是诊断OSAHS的金标准[2],该次研究采用PSG对2012年2月—2014年3月期间老年OSAHS进行了监测,探讨其在老年OSAHS中的应用价值,现报道如下。
1 资料与方法
1.1 一般资料
收集该院就诊的老年OSAHS病例,年龄>60周岁,所有受试者均有不同程度的打鼾、睡眠有窒息感、白天嗜睡等症状,经PSG检查,其中确证为OSAHS的病例共150例作为OSAHS组。收集同时期来该院进行健康体检的志愿者50例作为对照组。所有OSAHS组患者睡眠呼吸暂停低通气指数(AHI)>5。其中 OSAHS组男性89例,女性61例;年龄60~82岁,平均年龄(66.90±7.35)岁;合并肥胖45例,合并高血压67例,合并冠心病34例。对照组男性31例,女性19例;……
