EDITORIAL

1. Inhibition of poly(ADP-Ribose)polymerase:A promising strategy targeting pancreatic cancer with BRCAness phenotype

OPINION REVIEW

1. New drugs for the treatment of metastatic colorectal cancer

REVIEW

1. Extracellular vesicles:General features and usefulness in diagnosis and therapeutic management of colorectal cancer
2. Radiomics in hepatocellular carcinoma:A state-of-the-art review
3. Gut microbiota and immune system in liver cancer:Promising therapeutic implication from development to treatment
4. Role of mammalian target of rapamycin complex 2 in primary and secondary liver cancer
5. Regulatory role of the transforming growth factor-β signaling pathway in the drug resistance of gastrointestinal cancers

MINIREVIEWS

1. Novel perspective in pancreatic cancer therapy:Targeting ferroptosis pathway
2. Liver tumors in children with chronic liver diseases
3. Non-surgical treatment of hilar cholangiocarcinoma

ORIGINAL ARTICLE

1. Genome-wide CRISPR-Cas9 screening identifies that hypoxiainducible factor-1a-induced CBX8 transcription promotes pancreatic cancer progression via IRS1/AKT axis
2. Shuyu pills inhibit immune escape and enhance chemosensitization in hepatocellular carcinoma
3. Effects of dietary zinc deficiency on esophageal squamous cell proliferation and the mechanisms involved
4. Genetic variation of TGF-ΒR2 as a protective genotype for the development of colorectal cancer in men
5. Induction chemotherapy with albumin-bound paclitaxel plus lobaplatin followed by concurrent radiochemotherapy for locally advanced esophageal cancer
6. Preventive and inhibitive effects of Yiwei Xiaoyu granules on the development and progression of spasmolytic polypeptideexpressing metaplasia lesions

SYSTEMATIC REVIEWS

1. Colorectal cancer in Arab world:A systematic review
2. Cell-free DNA liquid biopsy for early detection of gastrointestinal cancers:A systematic review
3. Atezolizumab plus bevacizumab versus sorafenib or atezolizumab alone for unresectable hepatocellular carcinoma:A systematic review

META-ANALYSIS

1. Anatomical vs nonanatomical liver resection for solitary hepatocellular carcinoma:A systematic review and meta-analysis

LETTER TO THE EDITOR

1. Hepatocellular carcinoma biomarkers,an imminent need