Preface

1. Preface for Special Issue: Single-Cell and Spatially Resolved Omics

Perspective

1. Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application

Review Papers

1. Dissecting the brain with spatially resolved multi-omics
2. New discoveries in the field of metabolism by applying single-cell and spatial omics

Original Articles

1. Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer
2. Cux1+ proliferative basal cells promote epidermal hyperplasia in chronic dry skin disease identified by single-cell RNA transcriptomics
3. Single-cell analysis of cellular heterogeneity and interactions in the ischemia-reperfusion injured mouse intestine
4. Discovering metabolic vulnerability using spatially resolved metabolomics for antitumor small molecule-drug conjugates development as a precise cancer therapy strategy
5. The role of signaling crosstalk of microglia in hippocampus on progression of ageing and Alzheimer's disease
6. A Scd1-mediated metabolic alteration participates in liver responses to low-dose bavachin
7. Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis