EDITORIAL

1. Mission of the National Cancer Center Hospital in Japan to promote clinical trials for precision medicine
2. Genomic medicine in clinical practice: national genomic medicine program in Japan
3. Genomic medicine and cancer clinical trial in Thailand

PERSPECTIVE

1. Current and future trends in whole genome sequencing in cancer
2. Improving the value of molecular testing: current status and opportunities in colorectal cancer precision medicine

REVIEW

1. The evolution of cancer genomic medicine in Japan and the role of the National Cancer Center Japan
2. Emerging mechanisms and implications of cGAS-STING signaling in cancer immunotherapy strategies
3. The role of intestinal flora on tumorigenesis, progression,and the efficacy of PD-1/PD-L1 antibodies in colorectal cancer

ORIGINAL ARTICLE

1. Large-scale loss-of-function perturbations reveal a comprehensive epigenetic regulatory network in breast cancer